MN553 Unit 9 Practice Quiz Latest 2017

QuestionQuestion 1 1 / 1 pointUp to 21% of Asians are ultra-rapid 2D6 metabolizers, leading to:Question options:A need to monitor drugs metabolized by 2D6 for toxicityIncreased dosages needed of drugs metabolized by 2D6, such as the selective serotonin reuptake inhibitorsDecreased conversion of codeine to morphine by CYP 2D6The need for lowered dosages of drugs, such as beta blockersQuestion 2 1 / 1 pointRifampin is a nonspecific CYP450 inducer that may:Question options:Lead to toxic levels of rifampin and must be monitored closelyCause toxic levels of drugs, such as oral contraceptives, when coadministeredInduce the metabolism of drugs, such as oral contraceptives, leading to therapeutic failureCause nonspecific changes in drug metabolismQuestion 3 1 / 1 pointInhibition of P-glycoprotein by a drug such as quinidine may lead to:Question options:Decreased therapeutic levels of quinidineIncreased therapeutic levels of quinidineDecreased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and eliminationIncreased levels of a coadministered drug, such as digoxin, that requires P-glycoprotein for absorption and eliminationQuestion 4 1 / 1 pointWarfarin resistance may be seen in patients with VCORC1 mutation, leading to:Question options:Toxic levels of warfarin building upDecreased response to warfarinIncreased risk for significant drug interactions with warfarinLess risk of drug interactions with warfarinQuestion 5 1 / 1 pointPharmacogenetic testing is required by the U.S. Food and Drug Administration prior to prescribing:Question options:ErythromycinDigoxinCetuximabRifampinQuestion 6 1 / 1 pointCarbamazepine has a Black Box Warning recommending testing for the HLA-B*1502 allele in patients with Asian ancestry prior to starting therapy due to:Question options:Decreased effectiveness of carbamazepine in treating seizures in Asian patients with the HLA-B*1502 alleleIncreased risk for drug interactions in Asian patients with the HLA-B*1502 alleleIncreased risk for Stevens-Johnson syndrome in Asian patients with HLA-B*1502 AllelePatients who have the HLA-B*1502 allele being more likely to have a resistance to carbamazepineQuestion 7 1 / 1 pointA genetic variation in how the metabolite of the cancer drug irinotecan SN-38 is inactivated by the body may lead to:Question options:Decreased effectiveness of irinotecan in the treatment of cancerIncreased adverse drug reactions, such as neutropeniaDelayed metabolism of the prodrug irinotecan into the active metabolite SN-38Increased concerns for irinotecan being carcinogenicQuestion 8 1 / 1 pointA good history of herb and supplement use is critical before prescribing because approximately ____ % of patients in the United States are using herbal products.Question options:1053870Question 9 1 / 1 pointA potential harmful effect on patients who take some herbal medication is:Question options:ConstipationLead poisoningDiarrheaLife-threatening rashQuestion 10 1 / 1 pointA thorough understanding of herbs is critical to patient safety. An example is the use of cinnamon to treat type II diabetes. It is important the patient uses Ceylon cinnamon, as the commercially available cassia cinnamon contains:Question options:Coumadin, which may lead to bleeding problemsCoumarin, which can cause liver and kidney damageCinnamic aldehyde, which is toxic to the kidneyCinnamate eugenol, which is toxic to the liverQuestion 11 1 / 1 pointTraditional Chinese medicine utilizes yin (cooling) versus yang (warming) in assessing and treating disease. Menopause is considered a time of imbalance, therefore the Chinese herbalist would prescribe:Question options:Herbs which are yang in natureHerbs that are yin in natureGingerGolden sealQuestion 12 1 / 1 pointAccording to traditional Chinese medicine, if a person who has a fever is given a herb that is yang in nature, such as golden seal, the patient’s illness will:Question options:Get worseGet betterNot be adequately treatedNeed additional herbs to treat the yangQuestion 13 1 / 1 pointIn Ayurvedic medicine, treatment is based on the patient’s dominant dosha, which is referred to as the person’s:Question options:VataPittaKaphaPrakritiQuestion 14 1 / 1 pointWhen melatonin is used to induce sleep, the recommendation is that the patient:Question options:Take 10 mg 30 minutes before bed nightlyTake 1 to 5 mg 30 minutes before bed nightlyNot take melatonin more than three nights a weekCombine melatonin with zolpidem (Ambien) for the greatest impact on sleepQuestion 15 1 / 1 pointIn the United States, over-the-counter drugs are regulated by:Question options:No one. There is no oversight for over-the-counter medications.The U.S. Food and Drug Administration Center for Drug Evaluation and ResearchThe U.S. Drug Enforcement AdministrationMedWatchQuestion 16 1 / 1 pointAs drugs near the end of their patent, pharmaceutical companies may apply for the drug to change to over-the-counter status in order to:Question options:Get a new patent for the over-the-counter form of the drugLower the costs because most prescription benefit plans do not cover genericsMarket the drug to a whole new population, as they are able to market to patients instead of just providersContinue to make large profits from their blockbuster brand-name drugQuestion 17 1 / 1 pointThe ailment that generates the greatest over-the-counter annual drug sales is:Question options:ConstipationCough and coldsHeartburnAcute and chronic painQuestion 18 1 / 1 pointCommon over-the-counter pain relievers such as acetaminophen or ibuprofen:Question options:Are always safer for the patient than prescription pain medicationAre harmful if taken in higher than recommended amountsHave minimal interaction with prescription medicationsShould never be given to children unless recommended by their providerQuestion 19 1 / 1 pointWhen obtaining a drug history from Harold, he gives you a complete list of his prescription medications. He denies taking any other drugs, but you find that he occasionally takes aspirin for his arthritis flare ups. This is an example of:Question options:His appropriately only telling you about his regularly prescribed medicationsHis hiding information regarding his inappropriate use of aspirin from youA common misconception that intermittently taken over-the counter medications are not an important part of his drug historyA common misuse of over-the-counter aspirinQuestion 20 1 / 1 pointMichael asks you about why some drugs are over-the-counter and some are prescription. You explain that in order for a drug to be approved for over-the-counter use the drug must:Question options:Be safe and labeled for appropriate useHave a low potential for abuse or misuseBe taken for a condition the patient can reliably self-diagnoseAll of the above